ceesdekker.net Secrets
ceesdekker.net Secrets
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‘Certainly, which is about suitable. I look for a Actual physical understanding of biological programs in a bottom-up way. I do think you can distinguish 3 strains of research in my group at this time. The initial problems chromosome composition: How can you get a metre-prolonged DNA polymer folded and organised in this kind of microscopic mobile? We have produced visualisation approaches that allow for us to study how, one example is, SMC proteins loop DNA (online video on Youtube) to be able to Construct up chromosomes.
Our team scientific tests bacterial cell division and it is aiming to constitute a ‘base up biology’ in synthetic cells that may autonomously divide. Our main desire lies in mobile division, chromatin construction, and spatial control.
, Groningen scientists existing the effects of their efforts to create labs a lot more sustainable and provide techniques for other labs.
Sadly, For some time following Iijima’s report, the creation of thoroughly clean nanotubes was cumbersome. In 1996, on the other hand, the group of Richard Smalley at Rice College managed to provide solitary-walled carbon nanotubes at high produce. Soon following, I contacted Smalley, and we chose to sign up for forces to measure the transportation via a single carbon nanotube.
We create point-of-treatment diagnostics take a look at of neglected tropical disorders in resource-constrained options, according to Crspr/Cas9 detecting of pathogen’s DNA in human body fluids.
During the decades pursuing these discoveries, my exploration passions shifted to biophysics and nanobiology, and I turned fewer linked to the development of nanotube electronics. The focus of numerous scientists in the field also shifted to graphene (exactly where, funnily enough, the main graphene ribbons ended up referred to as ‘nanotubes which are Reduce open up alongside their length’) just after the invention of the two-dimensional product in 2004.
Since 2000 he moved to solitary-molecule biophysics and nanobiology, with research from DNA supercoiling reports of nucleosomes and DNA repair proteins to DNA translocation as a result of nanopores. Not too long ago his research has focused on researching cell division with microbes on chip, when his supreme desire is within the path of recognizing artificial cells.
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‘You should not just take into consideration the queries of tomorrow, but in addition take into account the inquiries with the working day immediately after tomorrow’
It was in the course of this era that Dekker performed research on magnetic spin methods and on noise in superconductors and semiconductors.
In 1993 he was appointed as Affiliate Professor at Delft College of Know-how. During the mid-nineteen nineties Dekker and his team accomplished good results with the discovery on the Digital Houses of carbon nanotubes, the 1st one-molecule transistor and various nanoscience.
2006, first demonstration of molecular sorting in a lab with a chip applying biomotors; discovery of nanobubbles in good-point out nanopores; and 1st estimate of electrokinetic Strength conversion in the nanofluidic channel
Visualization of unstained DNA nanostructures with Sophisticated in-focus transmission electron microscopy procedures
The biophysicist from Delft – who continues to be one of the most cited experts from the Netherlands For several years – normally takes his duty to contribute into the rationalization and popularisation of his operate on the border of physics and biology very seriously and on a regular basis seems within the media; Otherwise to look at his perform, then about the relationship concerning science and his Christian faith.